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Panama City, Panama
Skyscrapers, museums and old-town history to start the trip.
- From Panama City: Panama Canal and Monkey Island Tour
- Panama Old Town
- Presidential Palace
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Bocas del Toro, Panama
Laid-back Caribbean islands for solitude and beach time.
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Panama City, Panama
Back through the capital to prepare for the San Blas crossing.
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Cartí Sugtupu, Panama
Mainland port where the boats to San Blas leave.
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San Blas Islands, Panama
Island-hopping stay among the Guna Yala islands.
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Cartagena, Colombia
Colorful walled old city with a 16th-century fortress and lively nightlife.
Eat: Calle del Reloj
Do: San Felipe Castle, Plaza de los Coches, old city walls
- Cartagena: Sunset Cruise with Open Bar
- Cartagena City Walls
- Calle Santo Domingo
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Santa Marta, Colombia
Colonial old town and gateway to Tayrona Park.
Do: Old Town, Getsemani district, Cabo San Juan beach
- Santa Marta: Multi-Day Trek to The Lost City
- Parque de Los Novios
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Riohacha, Colombia
Small town with a historic centre and beaches nearby.
Do: Historic centre galleries, Playon Chico beach
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Uribia, Colombia
Quick stop in the cultural hub of the Wayúu people.
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Cabo de La Vela, Colombia
Remote desert village for kitesurfing and sweeping coastal views.
Do: El Cabo Beach, Pilón de Azúcar, Macuira National Park
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Buritaca, Colombia
Easy introduction to adventure tourism, with jungle and white-sand beach.
Do: Buritaca National Park, Tayrona Park trails
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Santa Marta, Colombia
A second night in Santa Marta before heading inland.
- Parque de Los Novios
- Basílica de Santa Marta
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Medellín, Colombia
Green mountain city with museums and nearby hikes.
Do: Parque Arvi, El Peñol, city museums
- Medellín: Comuna 13 Graffiti Tour with Local Guide
- Lleras Park
- Metropolitan Cathedral of Medellín
- Berrío Park
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San Gil, Colombia
Outdoor and nightlife town in the Santander mountains.
Do: Cerro de la Media Luna, mountain hikes, live music
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Barichara, Colombia
White-walled colonial village on a cliff face, great for slow walks.
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Bogotá, Colombia
Gold, history and the old district of La Candelaria.
Do: Museo del Oro, La Candelaria, Museo de Antioquia
- Bogotá: Colombian Coffee Tour with Farm Visit and Tastings
- La Macarena District
- National Park